Subtyping of panic disorder patients with bradycardia

Citation
J. Massana et al., Subtyping of panic disorder patients with bradycardia, EUR PSYCHIA, 16(2), 2001, pp. 109-114
Citations number
34
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Psychiatry,"Clinical Psycology & Psychiatry
Journal title
EUROPEAN PSYCHIATRY
ISSN journal
0924-9338 → ACNP
Volume
16
Issue
2
Year of publication
2001
Pages
109 - 114
Database
ISI
SICI code
0924-9338(200103)16:2<109:SOPDPW>2.0.ZU;2-R
Abstract
Purpose. Since clinical practice suggests that panic disorder may not be a homogeneous condition, a study was carried out to test the possible existen ce of different groups or subgroups of panic patients. Subjects and methods . Thirty-two panic patients (DSM-III-R) underwent lactate challenge in our laboratory and were assessed for heart rate, blood pressure. sweating and A cute Panic Inventory. Results. During the lactate challenge, patients compl aining mainly of 'cardiorespiratory' symptoms (N = 12) showed tachycardia a nd localized sweating. Conversely, patients complaining mainly of 'pseudone urological' symptoms (N = 16) showed bradycardia and generalized sweating. In both groups, Acute Panic Inventory scores were significantly higher duri ng than before the panic attack, but the distribution of the scores was mar kedly different. Discussion and Conclusion. The results suggest that panic disorder may be a heterogeneous condition. Implications of these results to other phobic disorders, to Klein's false suffocation alarm theory and to t he 'extended amygdala model' are discussed. (C) 2001 Editions scientifiques et medicales Elsevier SAS.