Study on the epidermal-dermal interactions during osteichthyan dermoskeleton development: a scale model

Authors
Citation
A. Quilhac, Study on the epidermal-dermal interactions during osteichthyan dermoskeleton development: a scale model, B S ZOOL FR, 125(4), 2000, pp. 321-332
Citations number
45
Language
FRANCESE
art.tipo
Article
Categorie Soggetti
Animal Sciences
Journal title
BULLETIN DE LA SOCIETE ZOOLOGIQUE DE FRANCE
ISSN journal
0037-962X → ACNP
Volume
125
Issue
4
Year of publication
2000
Pages
321 - 332
Database
ISI
SICI code
0037-962X(2000)125:4<321:SOTEID>2.0.ZU;2-X
Abstract
The aim of this study was to show the existence of epidermal-dermal interac tions during dermal scales regeneration to analyse their functions at the m orphological and cytological level and to study their molecular control. Th e chosen model is the teleost elasmoid scale of the cichlid fish Hemichromi s bimaculatus and of the zebrafish Danio rerio. The scales show several exp erimental advantages and particularly the faculty of regeneration. We have undertaken an histological study which suggests interactions betwee n the healing epidermis and the subepidermal mesenchyme during all steps of the regeneration process and an inductive role of the epidermis during ini tiation of this phenomenon. The spatio-temporal expression of die genes msx B, msxC, msxD, Bmp4, shh and ptcl suggest that they could have a role in th e epidermal and mesenchymal cells profileration and differentiation and in the formation of scale pattern.