Compliance, satisfaction, and quality of life of patients with colorectal cancer receiving home chemotherapy or outpatient treatment: a randomised controlled trial

Citation
Jm. Borras et al., Compliance, satisfaction, and quality of life of patients with colorectal cancer receiving home chemotherapy or outpatient treatment: a randomised controlled trial, BR MED J, 322(7290), 2001, pp. 826-828A
Citations number
22
Language
INGLESE
art.tipo
Article
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Journal title
BRITISH MEDICAL JOURNAL
ISSN journal
0959-535X → ACNP
Volume
322
Issue
7290
Year of publication
2001
Pages
826 - 828A
Database
ISI
SICI code
0959-535X(20010407)322:7290<826:CSAQOL>2.0.ZU;2-N
Abstract
Objective To compare chemotherapy given at home with outpatient treatment i n terms of colorectal cancer patients' safety, compliance: use of health se rvices, quality of life, and satisfaction with treatment. Design Randomised controlled trial. Setting Large teaching hospital. Participants 87 patients receiving adjuvant or palliative chemotherapy for colorectal cancer. Interventions Treatment with fluorouracil (with or without folinic acid or levamisole) at outpatient clinic or at home. Main outcome measures Treatment toxicity patients' compliance with treatmen t, quality of life, satisfaction with care, and use of health resources. Results 49 patients were treated at outpatient clinic and 45 at home. The t wo groups were balanced in terms of age, ses, site of cancer, and disease s tage. Treatment related toxicity was similar in the two groups (difference 7%, (95% confidence interval - 12% to 26%), but there were more voluntary: withdrawals from treatment in the outpatient group than in the home group ( 14% v 2%: difference 12% (1% to 24%)). There were no differences between gr oups in terms of quality of life scores during and after treatment. Levels of patient satisfaction were higher in the home treatment group, specifical ly with regard to information received and nursing care. There were no sign ificant differences in use of health services. Conclusions Home chemotherapy seemed an acceptable and safe alternative to hospital treatment for patients with colorectal cancer that mall improve co mpliance and satisfaction with treatment.