A case report of cribriform carcinoma of the pancreas with long time survival

Citation
W. Kimura et al., A case report of cribriform carcinoma of the pancreas with long time survival, HEP-GASTRO, 48(37), 2001, pp. 273-276
Citations number
9
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Gastroenerology and Hepatology","da verificare
Journal title
HEPATO-GASTROENTEROLOGY
ISSN journal
0172-6390 → ACNP
Volume
48
Issue
37
Year of publication
2001
Pages
273 - 276
Database
ISI
SICI code
0172-6390(200101/02)48:37<273:ACROCC>2.0.ZU;2-P
Abstract
A 62-year-old man had complained of left abdominal pain and tenderness and a body weight loss. Abdominal ultrasonography and computed tomography revea led homogeneous tumor with clear margin, and an irregular shape (3.5x2.0cm) in the body of the pancreas. Endoscopic retrograde cholangiopancreatograph y showed a shadow defect in the main pancreatic duct adjacent to the tumor, which suggested intraductal tumor spread. Distal pancreatectomy with splen ectomy and left paraaortic lymph node dissection was performed. Microscopic ally, the tumor showed microtubular carcinoma, which was characterized by a cribriform pattern, medullary growth, and little interstitium. The tumor w as encapsulated by a relatively thick fibrous capsule. The patient was disc harged uneventfully, and he is alive 33 months after operation without a di stinct sign of recurrence. In conclusion, cribriform carcinoma of the pancr eas has specific characteristics, such as good prognosis, expansive growth with little invasion, intraductal growth and spread without mucin productio n and histological marked cribriform pattern. This type of carcinoma should be classified as a new disease entity of carcinoma of the pancreas.