Synthesis of metabolically blocked paclitaxel analogues

Citation
Md. Wittman et al., Synthesis of metabolically blocked paclitaxel analogues, BIOORG MED, 11(6), 2001, pp. 809-810
Citations number
10
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry & Analysis
Journal title
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
ISSN journal
0960-894X → ACNP
Volume
11
Issue
6
Year of publication
2001
Pages
809 - 810
Database
ISI
SICI code
0960-894X(20010326)11:6<809:SOMBPA>2.0.ZU;2-G
Abstract
The stereospecific syntheses of the metabolically blocked 6-alpha -F, Cl, B r paclitaxel, and 6-alpha -F-10-acetyldocetaxel are described and in vitro and in vivo activity is presented. (C) 2001 Elsevier Science Ltd. All right s reserved.