Clinical significance of reverse redistribution on resting thallium-201 imaging in patients with vasospastic angina

Citation
A. Nakano et al., Clinical significance of reverse redistribution on resting thallium-201 imaging in patients with vasospastic angina, ANN NUCL M, 15(1), 2001, pp. 65-68
Citations number
13
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Radiology ,Nuclear Medicine & Imaging
Journal title
ANNALS OF NUCLEAR MEDICINE
ISSN journal
0914-7187 → ACNP
Volume
15
Issue
1
Year of publication
2001
Pages
65 - 68
Database
ISI
SICI code
0914-7187(200102)15:1<65:CSORRO>2.0.ZU;2-R
Abstract
To evaluate the clinical significance of reverse redistribution (RR) of res ting Tl-201 Single photon emission computed tomography (SPECT) in patients with vasospastic angina (VSA), we performed left ventriculography, coronary angiography and resting Tl-201-SPECT in 22 patients with VSA. Left ventric ulography showed abnormal wall motion in 17 of 22 patients (77%) and 37 of 154 segments. Thirty-one of these 37 segments (84%) were within the area pe rfused by coronary arteries showing acetylcholine-induced vasospasm. On Tl- 201 images, abnormal findings were observed in 11 of 22 patients (50%), and among them, 7 patients (32%) had RR. Seven of 37 segments (19%) having abn ormal regional wall motion had RR of Tl-201, and in 6 of these 7 segments ( 86%), accumulation of I-123-BMIPP was found to be reduced. We conclude that repetitive brief myocardial ischemia may cause myocardial injuries in patients with VSA, and that the presence of RR of Tl-201 indica tes the presence of myocardial injury in these patients.