Transcriptional regulation in lymphocytes

Authors
Citation
H. Okamura et A. Rao, Transcriptional regulation in lymphocytes, CURR OP CEL, 13(2), 2001, pp. 239-243
Citations number
55
Language
INGLESE
art.tipo
Review
Categorie Soggetti
Cell & Developmental Biology
Journal title
CURRENT OPINION IN CELL BIOLOGY
ISSN journal
0955-0674 → ACNP
Volume
13
Issue
2
Year of publication
2001
Pages
239 - 243
Database
ISI
SICI code
0955-0674(200104)13:2<239:TRIL>2.0.ZU;2-A
Abstract
Lymphocytes have been used to investigate many cellular processes, includin g lineage commitment, differentiation, proliferation and apoptosis. The tra nscription factors that mediate these processes are often expressed broadly in many cell types. The emerging theme is one of cell-type-specific regula tion, affecting not only the functional activation of transcription factors but also their access to appropriate regions of DNA.