K. Maruki et al., Effects of rat ventral and dorsal hippocampus temporal inactivation on delayed alternation task, BRAIN RES, 895(1-2), 2001, pp. 273-276
To determine the involvement of the hippocampal regions in a operant-type d
elayed alternation task of short delay or long delay, microinjections of mu
scimol into the hippocampus were used for temporal inactivation during the
behavioral test in each rat. Dorsal hippocampal inactivation impaired the c
orrect ratio of long delay. Ventral hippocampal inactivation showed no chan
ges in the correct ratio, however, it increased the tendency of perseverati
on in long delay. These findings suggest hippocampus has regional different
iation in delayed alternation task. (C) 2001 Elsevier Science B.V. All righ
ts reserved.