Coprinol, a new antibiotic cuparane from a Coprinus species

Citation
M. Johansson et al., Coprinol, a new antibiotic cuparane from a Coprinus species, Z NATURFO C, 56(1-2), 2001, pp. 31-34
Citations number
5
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Biochemistry & Biophysics
Journal title
ZEITSCHRIFT FUR NATURFORSCHUNG C-A JOURNAL OF BIOSCIENCES
ISSN journal
0939-5075 → ACNP
Volume
56
Issue
1-2
Year of publication
2001
Pages
31 - 34
Database
ISI
SICI code
0939-5075(200101/02)56:1-2<31:CANACF>2.0.ZU;2-M
Abstract
Coprinol, a new antibacterial cuparane, was isolated from fermentations of a Coprinus sp. Its biological activities were investigated and its structur e was elucidated by spectroscopic methods. The new antibiotic exhibited act ivity against multidrug-resistant Gram-positive bacteria in vitro. Two deri vatives were synthesized and their activities compared to the parent compou nd.