Wondonins A and B, new bis(dihydroxystyryl)imidazoles from a two-sponge association

Citation
J. Shin et al., Wondonins A and B, new bis(dihydroxystyryl)imidazoles from a two-sponge association, TETRAHEDR L, 42(10), 2001, pp. 1965-1968
Citations number
6
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON LETTERS
ISSN journal
0040-4039 → ACNP
Volume
42
Issue
10
Year of publication
2001
Pages
1965 - 1968
Database
ISI
SICI code
0040-4039(20010304)42:10<1965:WAABNB>2.0.ZU;2-E
Abstract
Wondonins A and B, two alkaloids of an unprecedented structural class, alon g with the previously described dihydroxystyryl sulfates, have been isolate d from an association of the sponges Poecillastra wondoensis and Jaspis sp. collected from Keomun Island, Korea. The structures of these compounds hav e been determined as imidazole alkaloids containing a bis(dihydroxystyrene) moiety by combined spectroscopic methods. The new compounds exhibited anti angiogenic activity against human umbilical vein endothelial cells. (C) 200 1 Elsevier Science Ltd. All rights reserved.