First isolation of Sarcocystis neurona from the South American opossum, Didelphis albiventris, from Brazil

Citation
Jp. Dubey et al., First isolation of Sarcocystis neurona from the South American opossum, Didelphis albiventris, from Brazil, VET PARASIT, 95(2-4), 2001, pp. 295-304
Citations number
24
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Veterinary Medicine/Animal Health
Journal title
VETERINARY PARASITOLOGY
ISSN journal
0304-4017 → ACNP
Volume
95
Issue
2-4
Year of publication
2001
Pages
295 - 304
Database
ISI
SICI code
0304-4017(20010226)95:2-4<295:FIOSNF>2.0.ZU;2-A
Abstract
Sarcocystis neurona was isolated from sporocysts from two of eight South Am erican opossums, Didelphis albiventris, from Brazil. Interferon gamma gene knock out (KO) mice fed sporocysts from two opossums developed neurologic s arcocystosis. S. neurona was demonstrated in the brains of infected KO mice by immunohistochemical staining with anti-S, neurona antibody. The parasit e was cultivated in cell culture and S. neurona DNA was isolated from cultu red merozoites. This is the first report of isolation of S. neurona from Br azil and the first report from its new host, D. albiventris. Published by E lsevier Science B.V.