Reduced arousals following obstructive apneas in infants sleeping prone

Citation
J. Groswasser et al., Reduced arousals following obstructive apneas in infants sleeping prone, PEDIAT RES, 49(3), 2001, pp. 402-406
Citations number
32
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Pediatrics,"Medical Research General Topics
Journal title
PEDIATRIC RESEARCH
ISSN journal
0031-3998 → ACNP
Volume
49
Issue
3
Year of publication
2001
Pages
402 - 406
Database
ISI
SICI code
0031-3998(200103)49:3<402:RAFOAI>2.0.ZU;2-D
Abstract
A decreased arousability and an increased risk for sudden infant death synd rome (SIDS) have been shown in infants sleeping prone. Obstructive apnea, a known risk factor for SIDS, is less often terminated by an arousal reactio n in infants than in adults. The effect of body position on the arousal rea ction to spontaneous respiratory events had not been previously studied in infants, The aim of our study was to see if body position has an influence on the frequency and delay of the arousal reaction to obstructive apnea. Al l obstructive events recorded during two successive nights in 20 infants sl eeping one night prone and one night supine were studied, During the supine recording 153 obstructive events were detected, and 217 were detected duri ng the prone session. Prone sleep was not associated with an increased freq uency of obstructive apneas. Total sleep time was 382 min (range, 283-456) supine and 423 min (range, 325-521) prone (p = 0.003). Obstructive events d uration was 6.5 s (range, 3-21.5) when sleeping supine and 8 s (range, 3.5- 30.5) when prone (p = 0.002). Behavioral arousal were found in 57.5% of obs tructive events recorded supine and in 31.3% of those seen prone (p < 0.001 ). Arousal occurred after 8 s (range, 0-21) from the start of the obstructi ons when supine and 10.5 s (range, 3.5-23.5) when prone (p = 0.001). Sighs were found in 34% of supine obstructive events and in 44.7% of those prone (p = 0.040). A reaction, i.e. arousal or sigh, was found in 91.5% of supine events and 76% of those prone (p < 0.001). We conclude that when sleeping supine, infants arouse to obstructive events more often and after shorter d elay than when prone.