ATTRIBUTABLE RISKS FOR KIDNEY CANCER IN NORTHERN ITALY

Citation
A. Tavani et al., ATTRIBUTABLE RISKS FOR KIDNEY CANCER IN NORTHERN ITALY, European journal of cancer prevention, 6(2), 1997, pp. 195-199
Citations number
27
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Oncology
ISSN journal
0959-8278
Volume
6
Issue
2
Year of publication
1997
Pages
195 - 199
Database
ISI
SICI code
0959-8278(1997)6:2<195:ARFKCI>2.0.ZU;2-3
Abstract
The percent population attributable risk (AR) for kidney cancer was es timated in relation to smoking habits, beta-carotene intake, history o f cystitis and family history of kidney cancer, using data from a case -control study conducted between 1985 and 1989 in Milan, northern Ital y. The data comprised 133 histologically confirmed cases of incident k idney cancer and 392 controls, admitted to hospital for a wide range o f acute, non-neoplastic, non-smoking-related diseases, On the basis of multivariate odds ratios (ORs), smoking habits accounted for about 26 % of cases, a low beta-carotene intake for 18%, a history of cystitis for 7%, and a family history of kidney cancer in first-degree relative s for 3% of cases, Ever smoking and low beta-carotene intake combined explained 38% of all kidney cancers, and the combination of these two factors plus a history of cystitis and a family history of kidney canc er explained 45% of the incidence of the disease, Thus, even if availa ble, dietary information was limited and the AR estimates were based o n somewhat arbitrary assumptions, A considerable proportion of kidney cancers could be avoided simply by eliminating smoking and increasing consumption of fruit and vegetables in this Italian population, This w ould mean that about 1,500 kidney cancer deaths every year in the whol e of Italy could be avoided.