Estrogen receptor transcription and transactivation - Basic aspects of estrogen action

Citation
S. Nilsson et Ja. Gustafsson, Estrogen receptor transcription and transactivation - Basic aspects of estrogen action, BREAST CA R, 2(5), 2000, pp. 360-366
Citations number
112
Language
INGLESE
art.tipo
Review
Categorie Soggetti
Oncology
Journal title
BREAST CANCER RESEARCH
ISSN journal
1465-542X → ACNP
Volume
2
Issue
5
Year of publication
2000
Pages
360 - 366
Database
ISI
SICI code
1465-542X(2000)2:5<360:ERTAT->2.0.ZU;2-1
Abstract
Estrogen signaling has turned out to be much more complex and exciting than previously thought; the paradigm shift in our understanding of estrogen ac tion came in 1996, when the presence of a new estrogen receptor (ER), ER be ta, was reported. An intricate interplay between the classical ER alpha and the novel ER beta is of paramount importance for the final biological effe ct of estrogen in different target cells.