S. Nilsson et Ja. Gustafsson, Estrogen receptor transcription and transactivation - Basic aspects of estrogen action, BREAST CA R, 2(5), 2000, pp. 360-366
Estrogen signaling has turned out to be much more complex and exciting than
previously thought; the paradigm shift in our understanding of estrogen ac
tion came in 1996, when the presence of a new estrogen receptor (ER), ER be
ta, was reported. An intricate interplay between the classical ER alpha and
the novel ER beta is of paramount importance for the final biological effe
ct of estrogen in different target cells.