Developing AIDS vaccine trials educational programs in Uganda

Citation
Jw. Mcgrath et al., Developing AIDS vaccine trials educational programs in Uganda, J ACQ IMM D, 26(2), 2001, pp. 176-181
Citations number
18
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Immunology
Journal title
JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
ISSN journal
1525-4135 → ACNP
Volume
26
Issue
2
Year of publication
2001
Pages
176 - 181
Database
ISI
SICI code
1525-4135(20010201)26:2<176:DAVTEP>2.0.ZU;2-W
Abstract
In preparation for HIV vaccine trials, data on a cohort's knowledge about v accines and vaccine studies are required so as to tailor educational materi als to adequately meet local needs. Interviews (n = 1,182) conducted as par t of a 3-year prospective study of Ugandan military men aged 18 to 30 years determined what information, in addition to standard trials information, w ould be required to ensure comprehension of trial procedures. The interview s highlighted four points: (1) the cohort has a lot of knowledge about vacc ines but conflates whether vaccines cure or prevent disease; (2) there is a general lack of knowledge about clinical trials procedures; (3) the desire to be protected from HIV/AIDS is a common reason for being willing to part icipate in a hypothetical vaccine trial; and (4) concern about side effects is a common reason for being unwilling to participate in a trial. These fo ur points guided the focus of the vaccine trials education, which used loca lly appropriate analogies to introduce complex unfamiliar concepts such as placebos and blinding. This case study highlights the value of incorporatin g baseline interviews to assess the educational needs of study populations.