In vitro development of resistance to six quinolones in Streptococcus pneumoniae, Streptococcus pyogenes, and Staphylococcus aureus

Citation
M. Boos et al., In vitro development of resistance to six quinolones in Streptococcus pneumoniae, Streptococcus pyogenes, and Staphylococcus aureus, ANTIM AG CH, 45(3), 2001, pp. 938-942
Citations number
44
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Microbiology
Journal title
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
ISSN journal
0066-4804 → ACNP
Volume
45
Issue
3
Year of publication
2001
Pages
938 - 942
Database
ISI
SICI code
0066-4804(200103)45:3<938:IVDORT>2.0.ZU;2-H
Abstract
Streptococcus pneumoniae, Streptococcus pyogenes, and Staphylococcus aureus isolates were exposed to subinhibitory MICs of ciprofloxacin, sparfloxacin , gatifloxacin, moxifloxacin, clinafloxacin, and gemifloxacin during a 10-d ay period. Subculturing led to resistance development, regardless of the in itial potencies of the quinolones. None of the quinolones was associated wi th a significantly slower rate of resistance development.