A practical route to quinolines from anilines

Citation
H. Tokuyama et al., A practical route to quinolines from anilines, HETEROCYCLE, 54(1), 2001, pp. 105-108
Citations number
3
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
HETEROCYCLES
ISSN journal
0385-5414 → ACNP
Volume
54
Issue
1
Year of publication
2001
Pages
105 - 108
Database
ISI
SICI code
0385-5414(20010101)54:1<105:APRTQF>2.0.ZU;2-X
Abstract
A practical route to quinoline from anilines through acid-mediated cyclizat ion of 3-(N-aryl-N-sulfonylamino)propionaldehydes has been developed. Treat ment of the cyclization products, dihydroquinoline intermediates with KOH i n DMSO leads to substituted quinolines.