Duration of ruptured membranes and vertical transmission of HIV-1: a meta-analysis from 15 prospective cohort studies

Authors
Andiman, W Boucher, M Bulterys, MB Burns, D Bryson, Y de Martino, M Farley, J Fowler, MG Galli, L Hanson, IC Kind, C Korber, B Kovacs, A Krogstad, P Landesman, S Lapointe, N Lemay, M Mandelbrot, L Mayaux, MJ Mellins, R Minkoff, H Mofenson, L Nielsen, K Newell, ML Pardi, G Peavy, H Peckham, C Read, JS Rother, C Rudin, C Scott, G Semprini, A Shearer, W Simpson, BJ Stek, A Thompson, B Tovo, PA Tuomala, R Van Dyke, RB Weedon, J Gabiano, C Harris, DR Lindsay, M Newell, ML Nielsen, K Peavy, HH Chan, L Easley, K Khammy, A Muenz, L Nugent, RP Durako, S Goodwin, S Mitchell, R Owen, W Van Dyke, R Widmayer, S Bardeguez, A Hanson, C Wiznia, A Luzuriaga, K Viscarello, R Ho, D Koup, R Chen, I Krogstad, P Mullins, J Wolinsky, S Walker, B Ammann, A Clapp, S McDonald, D Fauvel, M Hankins, C Samson, J Newell, ML Peckham, CS Thorne, CN Giaquinto, C Ruga, E De Rossi, A Truscia, D Grosch-Worner, I Schafer, A Mok, J Johnstone, F Jiminez, J de Alba, C Rodriguez, MCG Bates, I de Jose, I Hawkins, F Zapico, RM Pena, JM Garcia, JG Lopez, JRA Asensi-Botet, F Otero, MC Perez-Tamarit, D Moya, A Galbis, MJ Scherpbier, H Boer, K Bohlin, AB Lindgren, S Anzen, B Belfrage, E Lidin-Jansson, G Levy, J Barlow, P Hainaut, M Peltier, A Ferrazin, A De Maria, A Gotta, C Mur, A Vinolas, M Paya, A Lopez-Vilchez, MA Coll, O Fortuny, C Boguna, J Caro, MC Canet, Y Pardi, G Ravizza, M Semprini, E Castagna, C Fiore, S Guerra, B Lanari, M Bianchi, S Bovicelli, L Prati, E Zanelli, S Duse, M Soresina, A Scaraveli, G Stegagno, M De Santis, M Muggiasca, ML Vigano, A Spinillo, A Probizer, FR Bucceri, A Rancilio, L Taylor, GP Lyall, H Penn, Z Blott, M Valerius, NH Martinelli, P Buffolano, W Tibaldi, C Ziarati, N Pardi, G Semprini, A Ravizza, M Castagna, C Fiore, S Della Torre, M Parazzini, F Bovicelli, L Guerra, B Dallacasa, P Bianchi, S Duse, M Prati, E Zanelli, S Soresina, A Pachi, A Scaravelli, G Stegagno, M Mancuso, S De Santis, M Villa, P Conti, M Principi, N Muggiasca, M Marchisio, P Zara, C Spinillo, A Ravagni, F Vignali, M Bucceri, A Rossi, G Rancilio, L Selvaggi, L Greco, P Vimercati, A Massi, G Innocenti, T Fiscella, A Martinelli, P Sansone, M Benedetto, C Tibaldi, C Ziarati, N Tadrist, B Thevenieau, D Gondry, J Paulard, B Alisy, C Brault, D Tordjeman, N Mamou, J Rozan, M Colombani, D Pincemaille, O Salvetti, A Chabanier, C Hernandorena, X Leroy, J Schaal, J Balde, P Faucher, P Lachassinne, E Benoit, S Douard, D Hocke, C Barjot, P Brouard, J Delattre, P Stien, L Audibert, F Labrune, P Vial, M Mazy, F Sitbon, D Crenn-Hebert, C Floch-Tudal, C Akakpo, R Daveau, C Leblanc, A Cesborn, P Duval-Arnould, D Huraux-Rendu, C Lemerle, S Touboul, C Guerin, M Maingueneau, C Reyaud, I Rousseau, T Ercoil, V Lanza, M Denavit, M Garnier, J Lahsinat, K Pia, P Allouche, C Nardou, M Grall, F May, A Dallot, M Lhuillier, P Cecile, W Mezin, R Balde, P Bech, A Lobut, J Algava, G Dermesay, AC Busuttil, R Jacquemot, M Bader-Meunier, B Fridman, S Codaccioni, X Maxingue, F Thomas, D Alain, J De Lumley, L Tabaste, J Salin, PB Seaume, H Guichard, A Kebaill, K Roussouly, C Botto, C De Lanete, A Wipff, P Cravello, L De Boisse, P Leclaire, M Michel, G Crumiere, C Lefevre, V Le Lorier, B Pauly, I Robichez, B Seguy, D Delhinger, M Rideau, F Talon, P Benos, P Huret, C Nicolas, J Heller-Roussin, B Saint-Leger, S Delaporte, M Hubert, C De Sarcus, B Karoubi, P Mechinaud, F Bertcrottiere, D Bongain, A Monpoux, F De Gennes, C Devianni, F Nisand, I Rousset, M Karoubi, P Mouchnino, G Muray, J Munzer, M Quereux, C Brossard, V Clavier, B Allemon, M Rotten, D Stephan, J Varlet, M Guyot, B Narcy, P Bardinet, F De Caunes, F Jeny, R Robin, M Boulley, AR Savey, L Berrebi, A Tricoire, J Borderon, J Fignon, A Guillot, F Maria, B Broyard, A Chitrit, Y Firtion, G Mandelbrot, L Pillet, ML Parat, S Boissinot, C Garec, N Levine, M Ottenwalter, A Schaller, F Vilmer, E Coupotin, C Brunner, C Ciraru-Vigneron, N Hatem-Gantzer, G Heller-Roussin, B Fritel, X Wallet, A Bouille, J Milliez, J Mrejen, DB Dermer, E Noseda, G Bardou, D Cressaty, J Francoual, C Moncomble, CC Cohen, H Blanche, S Bastion, H Benifla, J Benkhatar, F Berkane, N Herve, F Ronzier, M Mayaux, MJ Blanche, S Mandelbrot, L de Martino, M Tovo, PA Galli, L Gabiano, C Ferraris, G Rancilio, L Bucceri, A Garetto, S Palomba, E Riva, C Vierucci, A de Luca, M Farina, S Fundaro, C Genovese, O Mereu, G Forni, GL Casadei, A Zuccotti, GV Riva, E Cellini, M Baraldi, C Consolini, R Palla, G Ruggeri, M Ciccimarra, F Guarino, A Osimani, P Banaglia, G Romano, A Lanari, M De Mattia, D Caselli, D Boni, S Dell'Erba, G Bassanetti, F Sticca, M Timpano, C Magnani, C Salvatore, C Lipreri, R Tornaghi, R Pinzani, R Cecchi, MT Bezzi, T Battisti, L Bresciani, E Gattinara, GC Nasi, C Pellegatta, A Mazza, A Baldi, F Ruga, E Altobelli, R Deiana, M Colnaghi, C Tarallo, L Tondo, U Anastasio, E Duse, M Chiriaco, PG Ruggeri, C Scott, G Hutto, C O'Sullivan, M Malmsberry, A Willoughby, A Burns, D Goedert, J Landesman, S Minkoff, H Mendez, H Holman, S Rubinstein, A Durako, S Muenz, L Goodwin, S Nesheim, S Lindsay, M Lee, F Nahmias, A Sawyer, M Vink, P Farley, J Alger, L Abrams, E Bamji, M Lambert, G Schoenbaum, E Thomas, P Weedon, J Palumbo, P Bardeguez, A Denny, T Oleske, J Bulterys, M SImonds, R Ethier-Ives, J Rogers, M Schluchter, M Kutner, M Kaplan, S Kattan, M Lipshultz, S Mellins, R Shearer, W Peavy, H Sopko, G Sloand, E Wu, M Kind, C Nadal, D Rudin, C Siegrist, CA Wyler, CA Cheseaux, JJ Aebi, C Gnehm, H Schubiger, G Klingler, J Hunziker, U Kuchler, H Gianinazzi, M Buhlmann, U Rudin, C Biedermann, K Lauper, U Irion, O Brunelli, A Spoletini, G Schreyer, A Kind, C Hosli, I Saurenmann, E Drack, G Isenschmid, M Poorbeik, M Schupbach, J Perrin, L Erb, P Joller, H Bryson, Y Dillon, M Nielsen, K Boyer, P Liao, D Keller, M Deveikis, A Kovacs, A Stek, A Chan, L Khoury, M Diaz, C Pacheco-Acosta, E Tuomala, R Cooper, E Mesthene, D Pitt, J Higgins, A Landesman, S Mendez, H Moroso, G Rich, K Turpin, D Shearer, W Hanson, C Cooper, N Fowler, MG Nugent, RP Davenny, K Thompson, B Andiman, W Simpson, J
Citation
W. Andiman et al., Duration of ruptured membranes and vertical transmission of HIV-1: a meta-analysis from 15 prospective cohort studies, AIDS, 15(3), 2001, pp. 357-368
Citations number
29
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Immunology
Journal title
AIDS
ISSN journal
0269-9370 → ACNP
Volume
15
Issue
3
Year of publication
2001
Pages
357 - 368
Database
ISI
SICI code
0269-9370(20010216)15:3<357:DORMAV>2.0.ZU;2-Z
Abstract
Objective: To test the a priori hypothesis that longer duration of ruptured membranes is associated with increased risk of vertical transmission of HI V. Design: The relationship between duration of ruptured membranes and vertica l transmission of HIV was evaluated in an individual patient data meta-anal ysis. Methods: Eligible studies were prospective cohort studies including at leas t 100 mother-child pairs, from regions where HIV-infected women are counsel led not to breastfeed. Analyses were restricted to vaginal deliveries and n on-elective Cesarean sections; elective Cesarean section deliveries (those performed before onset of labour and before rupture of membranes) were excl uded. Results: The primary analysis included 4721 deliveries with duration of rup tured membranes less than or equal to 24 h. After adjusting for other facto rs known to be associated with vertical transmission using logistic regress ion analysis to assess the strength of the relationship, the risk of vertic al HIV transmission increased approximately 2% with an increase of 1 h in t he duration of ruptured membranes [adjusted odds ratio, 1.02; 95% confidenc e interval, 1.01-1.04; for each 1 h increment]. There were no significant i nteractions of duration of ruptured membranes with study cohort or with any of the covariates, except maternal AIDS. Among women diagnosed with AIDS, the estimated probability of transmission increased from 8% to 31% with dur ation of ruptured membranes of 2 h and 24 h respectively (P < 0.01). Conclusions: These results support the importance of duration of ruptured m embranes as a risk factor for vertical transmission of HIV and suggest that a diagnosis of AIDS in the mother at the time of delivery may potentiate t he effect of duration of ruptured membranes. (C) 2001 Lippincott Williams & Wilkins.