Jm. Bennett et al., The identification of alpha-ketoamides as potent inhibitors of hepatitis Cvirus NS3-4A proteinase, BIOORG MED, 11(3), 2001, pp. 355-357
Peptides based upon the non-prime side residues of the NS4A-4B cleavage sit
e of hepatitis C virus (HCV) NS3-4A proteinase containing an alpha -ketoami
de moiety in place of the scissile amide bond are potent inhibitors of this
enzyme. (C) 2001 Elsevier Science Ltd. All rights reserved.