Mortality in dry-cleaning workers: An update

Citation
Am. Ruder et al., Mortality in dry-cleaning workers: An update, AM J IND M, 39(2), 2001, pp. 121-132
Citations number
54
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Envirnomentale Medicine & Public Health
Journal title
AMERICAN JOURNAL OF INDUSTRIAL MEDICINE
ISSN journal
0271-3586 → ACNP
Volume
39
Issue
2
Year of publication
2001
Pages
121 - 132
Database
ISI
SICI code
0271-3586(200102)39:2<121:MIDWAU>2.0.ZU;2-E
Abstract
Background A cohort of 1,708 dry-cleaning workers identified from union rec ords was exposed to perchloroethylene (PCE), a known animal carcinogen and probable human carcinogen, for at least 1 year before 1960. Many workers al so had exposure to Stoddard solvent, a petroleum-based dry-cleaning solvent . Methods Vital status was updated through 1996 and life table analyses condu cted. Results The cohort had excess cancer mortality (271 deaths, standardized mo rtality ratio [SMR] 1.25, 95% confidence interval [CI] 1.11-1.41). Elevated SMRs for tongue, bladder; esophagus, intestine, lung and cervical cancer; pneumonia, and diseases of the stomach and duodenum were statistically sign ificant. Conclusion The current study confirms findings of prior updates and other s tudies that dry-cleaning workers have excess cancer mortality at several si tes. Although important lifestyle and socioeconomic risk factors exist for both cervical and esophageal cancer mortality excesses of these sites in th e PCE only subcohort and among workers with longer duration of PCE exposure suggest an association with PCE exposure. Am. J. Ind. Med. 39:121-132, 200 1. (C) 2001 Wiley-Liss, Inc.