Flavonol glycosides and steroidal saponins from the leaves of Cestrum nocturnum and their cytotoxicity

Citation
Y. Mimaki et al., Flavonol glycosides and steroidal saponins from the leaves of Cestrum nocturnum and their cytotoxicity, J NAT PROD, 64(1), 2001, pp. 17-22
Citations number
13
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
0163-3864 → ACNP
Volume
64
Issue
1
Year of publication
2001
Pages
17 - 22
Database
ISI
SICI code
0163-3864(200101)64:1<17:FGASSF>2.0.ZU;2-N
Abstract
Phytochemical analysis of the leaves of Cestrum nocturnum (Solanaceae) resu lted in the isolation of two new flavonol glycosides (1, 2) and seven stero idal saponins (3-9), including four new ones (4, 6, 7, and 9). The structur es of the new compounds were determined by spectroscopic analysis, includin g 2D NMR data, and the results of hydrolytic cleavage. Cytotoxic activities of the isolated compounds against human oral squamous cell carcinoma-(HSC- 2) cells and normal human gingival fibroblasts are reported.