Origin of enzootic intranasal tumor in the goat (Capra hircus): A glycohistochemical approach

Citation
P. Scocco et al., Origin of enzootic intranasal tumor in the goat (Capra hircus): A glycohistochemical approach, VET PATH, 38(1), 2001, pp. 98-104
Citations number
23
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Veterinary Medicine/Animal Health","Medical Research Diagnosis & Treatment
Journal title
VETERINARY PATHOLOGY
ISSN journal
0300-9858 → ACNP
Volume
38
Issue
1
Year of publication
2001
Pages
98 - 104
Database
ISI
SICI code
0300-9858(200101)38:1<98:OOEITI>2.0.ZU;2-B
Abstract
Enzootic intranasal tumor (EIT) appears glandular in type and has recently been classified as an adenocarcinoma of low malignancy. The aim of this stu dy was to characterize the secretion of surface glycoconjugates (GCs) in EI T and in normal respiratory and olfactory mucosae of the goat by means of c onventional and lectin histochemistry. in order to shed light on the histog enesis of EIT. Morphologic and ultrastructural investigations showed two gr owth types of EIT: i.e., tubular and papillary patterns. Conventional histo chemistry revealed the presence of neutral and carboxylated GCs in the olfa ctory glands and in the tubular part of EIT, as well neutral and sulphated GCs in the respiratory glands and in the papillary part of EIT, suggesting that the papillary pattern tumor arises from the respiratory glands, wherea s the tubular portion of EIT arises from the olfactory glands. Lectin histo chemistry gave further information on the expressed GCs.