Highly efficient ligands for palladium-catalyzed asymmetric alkylation of ketone enolates

Citation
Sl. You et al., Highly efficient ligands for palladium-catalyzed asymmetric alkylation of ketone enolates, ORG LETT, 3(2), 2001, pp. 149-151
Citations number
42
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC LETTERS
ISSN journal
1523-7060 → ACNP
Volume
3
Issue
2
Year of publication
2001
Pages
149 - 151
Database
ISI
SICI code
1523-7060(20010125)3:2<149:HELFPA>2.0.ZU;2-X
Abstract
[GRAPHICS] Ferrocene modified chiral pocket ligands have been studied in the palladium catalyzed asymmetric alkylation of simple ketone enolates, in which (R,R,S p,Sp)-1 containing two pairs of matched chiralities, central chirality and planar chirality, behaved very efficiently in this reaction and up to 95% e e value was achieved.