Ga-67 citrate scintigraphy in the management of malignant lymphomas is well
established. It cannot, however, differentiate malignant from benign lesio
ns because this agent also accumulates in benign inflammatory lesions. The
authors present a case of increased I-123 IMP uptake on both early and dela
yed SPECT images in a patient with malignant lymphoma of the central nervou
s system. Results show that I-123 IMP SPECT can help differentiate malignan
t lymphoma from benign lesions and other malignant brain tumors.