The relationship of psychiatric comorbidity to treatment outcomes in methadone maintained patients

Citation
Js. Cacciola et al., The relationship of psychiatric comorbidity to treatment outcomes in methadone maintained patients, DRUG AL DEP, 61(3), 2001, pp. 271-280
Citations number
32
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Neurosciences & Behavoir
Journal title
DRUG AND ALCOHOL DEPENDENCE
ISSN journal
0376-8716 → ACNP
Volume
61
Issue
3
Year of publication
2001
Pages
271 - 280
Database
ISI
SICI code
0376-8716(20010201)61:3<271:TROPCT>2.0.ZU;2-U
Abstract
The authors examined the relationship of comorbid non-substance use psychia tric disorders to preadmission problem status and treatment outcomes in 278 methadone maintenance patients. Recent admissions were assigned DSM-III-R Axis I and II diagnoses according to structured diagnostic interviews. The Addiction Severity Index was administered at admission to assess past and c urrent substance use and psychosocial problems and again 7 months later. Tr eatment retention and month 7 drug urinalysis results were also obtained. A cross substance use and psychosocial domains, participants showed significa nt and comparable levels of improvement regardless of comorbidity. Comorbid participants received more concurrent psychiatric treatment which may have accounted for the lack of differential improvement among groups. Neverthel ess. psychiatric comorbidity was associated with poorer psychosocial and me dical status at admission and follow-up and participants with the combinati on of Axis I and II comorbidity had the most severe problems. Admission and month 7 substance use were, for the most part. not related to psychiatric comorbidity, although there was a trend indicating more treatment attrition for participants with personality disorders. (C) 2001 Elsevier Science Ire land Ltd. All rights reserved.