Thermodynamics of transfer of amino acids from water to aqueous sodium sulfate

Citation
Mn. Islam et Rk. Wadi, Thermodynamics of transfer of amino acids from water to aqueous sodium sulfate, PHYS CHEM L, 39(1), 2001, pp. 77-84
Citations number
25
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
PHYSICS AND CHEMISTRY OF LIQUIDS
ISSN journal
0031-9104 → ACNP
Volume
39
Issue
1
Year of publication
2001
Pages
77 - 84
Database
ISI
SICI code
0031-9104(2001)39:1<77:TOTOAA>2.0.ZU;2-F
Abstract
The solubilities of amino acids at 288.15, 298.15 and 308.15 K in water and aqueous sodium sulfate have been determined as a function of electrolyte c oncentration (0.5, 1.0, 1.5 mol/kg of water). It has been observed that sod ium sulfate renders amino acids less soluble. The free energies of transfer of amino acids from water to aqueous sodium sulfate have been calculated f rom the solubility data. The enthalpies and entropies of transfer have also been estimated. The solubility and the thermodynamics of transfer data man ifest that sodium sulfate generates favourable interaction between nonpolar groups of amino acids. If applied to proteins, it seems to stabilize the p rotein native globular structure by enhancing the intramolecular nonpolar-n onpolar group interactions.