A novel ferrocenyl diselenide for the catalytic asymmetric aryl transfer to aldehydes

Citation
C. Bolm et al., A novel ferrocenyl diselenide for the catalytic asymmetric aryl transfer to aldehydes, NEW J CHEM, 25(1), 2001, pp. 13-15
Citations number
42
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry
Journal title
NEW JOURNAL OF CHEMISTRY
ISSN journal
1144-0546 → ACNP
Volume
25
Issue
1
Year of publication
2001
Pages
13 - 15
Database
ISI
SICI code
1144-0546(2001)25:1<13:ANFDFT>2.0.ZU;2-Y
Abstract
An oxazolinyl ferrocenyl diselenide was synthesised by directed ortho-metal ation and used as catalyst precursor in the asymmetric addition of diethyl- and diphenylzinc to various aldehydes, yielding synthetically useful secon dary alcohols, of which some are difficult to access using other catalytic methodologies. Enantioselectivities of up to 44% for the former and up to 8 5% for the latter transformations were obtained.