Correlation between progression of spinal deformity and pulmonary functionin Duchenne muscular dystrophy

Citation
T. Yamashita et al., Correlation between progression of spinal deformity and pulmonary functionin Duchenne muscular dystrophy, J PED ORTH, 21(1), 2001, pp. 113-116
Citations number
11
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Ortopedics, Rehabilitation & Sport Medicine
Journal title
JOURNAL OF PEDIATRIC ORTHOPAEDICS
ISSN journal
0271-6798 → ACNP
Volume
21
Issue
1
Year of publication
2001
Pages
113 - 116
Database
ISI
SICI code
0271-6798(200101/02)21:1<113:CBPOSD>2.0.ZU;2-5
Abstract
The purpose of this study was to investigate how age at and value of the pl ateau of vital capacity (VC plateau) correlate with the severity of the pro gression of spinal deformity in patients with Duchenne muscular dystrophy ( DMD). Changes in spinal deformity and pulmonary function in 36 DMD patients were examined in a retrospective longitudinal study. Patterns of progressi on of spinal deformity were classified into three types according to Oda's classification. Of the 32 patients who showed spinal deformity, six were cl assified as type 1, 19 as type 2, and seven as type 3, The correlation betw een the patterns of progression of spinal deformity and the VC plateau was examined using a discriminant analysis. Rapid and severe progression of spi nal deformity could be expected in patients whose VC plateau was less than 1,900 mt and in those in which it occurred before age 14 years. Thus VC pla teau may be an indicator of the severity of the progression of spinal defor mity in DMD patients.