Infantile perineal protrusion: A statistical, clinical, and histopathologic study

Citation
R. Konta et al., Infantile perineal protrusion: A statistical, clinical, and histopathologic study, DERMATOLOGY, 201(4), 2000, pp. 316-320
Citations number
7
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Dermatology
Journal title
DERMATOLOGY
ISSN journal
1018-8665 → ACNP
Volume
201
Issue
4
Year of publication
2000
Pages
316 - 320
Database
ISI
SICI code
1018-8665(2000)201:4<316:IPPASC>2.0.ZU;2-S
Abstract
Background: Review of the literature of the peculiar nodule in the perineum of female infants disclosed that the analysis of incidence by gender, obse rvation of the course, histopathologic assessment, and the pathogenesis of the abnormality was suboptimal. Objective: We therefore planned to study a large number of children to analyze the incidence by gender, the course, an d the pathogenesis of the peculiar perineal nodules. Methods: Of 500 childr en (224 boys and 276 girls) who ranged from newborn to 11 years of age, occ urrence of the perineal nodules was checked. When nodules were found, the s ite, shape, size, number, and the onset were examined. Histopathologic exam ination and observation of the course were carried out in some cases. Resul ts: None of the boys in our population had nodules, but 13% of the girls di d. These lesions always occurred as a single peanut-, hen's crest-, or tong ue tip-shaped nodule on the perineal midline, and 93% of the lesions had be en present since birth. Histologically, the nodule was an outward projectio n of essentially normal, redundant skin, showing no evidence of lichen scle rosus et atrophicus. Conclusion: In view of these findings, we conclude tha t perineal nodules are a kind of developmental anomaly occurring mostly in girls. Copyright (C) 2000 S. Karger G, Basel.