Novel membrane materials having EEE derivatives as a chiral recognition site

Citation
M. Yoshikawa et al., Novel membrane materials having EEE derivatives as a chiral recognition site, EUR POLYM J, 37(2), 2001, pp. 335-342
Citations number
18
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
EUROPEAN POLYMER JOURNAL
ISSN journal
0014-3057 → ACNP
Volume
37
Issue
2
Year of publication
2001
Pages
335 - 342
Database
ISI
SICI code
0014-3057(200102)37:2<335:NMMHED>2.0.ZU;2-J
Abstract
Molecularly imprinted polymeric membranes with tripeptide residue H-Glu(OBz l)-Glu(OBzl)-Glu(OBzl)-CH2-(EEE) were prepared during the membrane preparat ion process in the presence of a print molecule. The Boc-L-Trp imprinted po lymeric membranes thus obtained showed adsorption selectivity toward the pr int molecule analogue, Acr-Trp. From the adsorption isotherms of Ac-Trp's, the chiral recognition site, which was formed by the print molecule in the membrane preparation process, exclusively recognizes Ac-L-Trp, and the oppo site isomer, Ac-D-Trp, is rejected. Enantioselective electrodialysis was at tained and the separation factor toward L-isomer reached 5.0, reflecting ad sorption selectivity. The membrane performance, such as the amount of enant iomer recognized and flux value of enantioselective electrodialysis, are gr eatly dependent on the concentration of tripeptide residues in the membrane . (C) 2000 Elsevier Science Ltd. All rights reserved.