The effects of hyperglycemia on skin graft survival in the burn patient

Citation
A. Mowlavi et al., The effects of hyperglycemia on skin graft survival in the burn patient, ANN PL SURG, 45(6), 2000, pp. 629-632
Citations number
10
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Surgery
Journal title
ANNALS OF PLASTIC SURGERY
ISSN journal
0148-7043 → ACNP
Volume
45
Issue
6
Year of publication
2000
Pages
629 - 632
Database
ISI
SICI code
0148-7043(200012)45:6<629:TEOHOS>2.0.ZU;2-O
Abstract
The authors elected to determine the relative effects of hyperglycemia and/ or elevated wound Gram-positive bacterial counts on success of skin graft s urvival in 74 burn patients. Results of serum glucose and quantitative woun d biopsies on the day of admission and on postoperative day 4 were charted. Cases were separated into the following groups for analysis: normoglycemia plus normal bacterial counts, elevated bacterial counts only, hyperglycemi a only, and hyperglycemia plus elevated bacterial counts. Successful graft "take" was defined as survival of 80% to 100% of the grafted area as assess ed on postoperative day 4. Significant results included decreased incidence of graft take for groups with hyperglycemia only (62.5%), elevated bacteri al counts only (63.3%), as well as hyperglycemia plus elevated bacterial co unts (54.5%) when compared with the group with normoglycemia plus normal ba cterial counts (92.8%; p = 0.020, p = 0.042, p = 0.012 respectively) for ph ysiological parameters measured on postoperative day 4 only. Additionally, incidence of graft take was reassessed and found to be decreased significan tly in groups with hyperglycemia (60.0%) vs. groups with normoglycemia (84. 6%), regardless of Gram-positive bacterial counts (p = 0.034).