A functional map of cervical metastases from oral squamous cell carcinoma

Citation
L. Gray et al., A functional map of cervical metastases from oral squamous cell carcinoma, ACT OTO-LAR, 120(7), 2000, pp. 885-890
Citations number
9
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Otolaryngology,"da verificare
Journal title
ACTA OTO-LARYNGOLOGICA
ISSN journal
0001-6489 → ACNP
Volume
120
Issue
7
Year of publication
2000
Pages
885 - 890
Database
ISI
SICI code
0001-6489(200010)120:7<885:AFMOCM>2.0.ZU;2-M
Abstract
A visual summary of underlying patterns in metastases from oral squamous ce ll carcinoma (SCC) was created by the mathematical technique of multidimens ional scaling (MDS). MDS creates a "functional" map of the neck, such that adjacent sites share similar probabilities of disease. We mapped the metast ases from 130 sequential cases of oral SCC in the UK. Binary Euclidean dist ances were calculated From tallies of metastases at all possible pairs of n eck levels (I-V on each side) for each of seven different primary sites: bu ccal mucosa. lower alveolus, floor of mouth, ventral tongue/floor of mouth, lateral tongue, retromolar trigone, and oropharynx. A two-dimensional func tional map of the neck was made from these distances. The map explains 82% of the input data (p < 0.01). This is the first functional mapping of neck levels. The technique can now be used to summarize and compare patterns of metastases in different populations.