Case Report: Human neonatus with spina bifida, clubfoot, situs inversus totalis and cerebral deformities: sequence or accident?

Citation
J. Piegger et al., Case Report: Human neonatus with spina bifida, clubfoot, situs inversus totalis and cerebral deformities: sequence or accident?, ANN ANATOMY, 182(6), 2000, pp. 577-581
Citations number
20
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Experimental Biology
Journal title
ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER
ISSN journal
0940-9602 → ACNP
Volume
182
Issue
6
Year of publication
2000
Pages
577 - 581
Database
ISI
SICI code
0940-9602(200011)182:6<577:CRHNWS>2.0.ZU;2-C
Abstract
An unreported coincidence of malformations has been studied by anatomical d issection in a mature male fetus. Auxiliary, this fetus was examined by com puted tomography and the skeletal malformations were three-dimensionally re constructed. The organs of the thorax as well as of the abdomen showed a vi sceral inversion. In the lumbar region, a hyperkyphosis was detected in add ition to a split-notochord. A hydrocephalus internus with enlarged lateral ventricles and an agenesis of the corpus callosum were apparent. The lower extremities were dystrophic with both showing a talipes equinovarus-deforma tion. Following the case report, we discuss if this is coincidental or mani festations in consequence of one defect.