Transient expression of synaptogyrin in the ganglionic eminence of the human fetal brain

Citation
N. Ulfig et al., Transient expression of synaptogyrin in the ganglionic eminence of the human fetal brain, ANN ANATOMY, 182(6), 2000, pp. 505-508
Citations number
15
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Experimental Biology
Journal title
ANNALS OF ANATOMY-ANATOMISCHER ANZEIGER
ISSN journal
0940-9602 → ACNP
Volume
182
Issue
6
Year of publication
2000
Pages
505 - 508
Database
ISI
SICI code
0940-9602(200011)182:6<505:TEOSIT>2.0.ZU;2-9
Abstract
The ganglionic eminence (GE) representing a conspicuous bulb-like elevation of the telencephalic proliferative zone has recently been shown to be invo lved in the establishment of cortical connections. This study demonstrate s the presence of synaptogyrin-immunoreactivity in a large number of cell bo dies of the human GE between 12 and 20 weeks of gestation. From the 20(th) week onwards synaptogyrin expression sharply declines. No immunoreactive st ructures are detectable in the 23(rd) week or later. As the CE persists nea rly throughout the entire fetal period these results show that its neuroche mical features change distinctly in the course of development. The synaptog yrin-immunoreactive GE-cells may form an early corticopedal connection whic h provides a scaffold for outgrowing cortical axons.