Reversal of intra-amniotic Chlamydia trachomatis antigen status

Citation
H. Yoshida et al., Reversal of intra-amniotic Chlamydia trachomatis antigen status, GYNECOL OBS, 50(4), 2000, pp. 278-280
Citations number
8
Language
INGLESE
art.tipo
Article
Categorie Soggetti
da verificare
Journal title
GYNECOLOGIC AND OBSTETRIC INVESTIGATION
ISSN journal
0378-7346 → ACNP
Volume
50
Issue
4
Year of publication
2000
Pages
278 - 280
Database
ISI
SICI code
0378-7346(2000)50:4<278:ROICTA>2.0.ZU;2-F
Abstract
Chlamydia trachomatis (CT) infection in pregnant women is related to unfavo rable obstetric outcomes such as prematurity, intrauterine growth retardati on, and stillbirth. A 22-year-old woman underwent transabdominal amniocente sis at 16 weeks of gestation (GW). A CT antigen test using polymerase chain reaction in the amniotic fluid was found to be positive, though the patien t had no symptom of infection. Beginning at 20 GW, clarithromycin was orall y administered at a dose of 400 mg/day for 2 weeks. The CT antigen test in amniotic fluid at 28 GW turned to a negative result. A female baby was vagi nally born at 38 GW by spontaneous labor. The CT antigen test of her gastri c contents showed a negative result and anti-CT IgM in umbilical cord blood was negative. Neither respiratory distress, pneumonia, nor conjunctivitis was detected. To the best of our knowledge, this case is the first report s howing the reversal of the intra-amniotic CT antigen status by antibiotic t reatment. Copyright (C) 2000 S. Karger AG, Basel.