Regulation of carbon catabolism in Bacillus species

Citation
J. Stulke et W. Hillen, Regulation of carbon catabolism in Bacillus species, ANN R MICRO, 54, 2000, pp. 849-880
Citations number
198
Language
INGLESE
art.tipo
Review
Categorie Soggetti
Microbiology
Journal title
ANNUAL REVIEW OF MICROBIOLOGY
ISSN journal
0066-4227 → ACNP
Volume
54
Year of publication
2000
Pages
849 - 880
Database
ISI
SICI code
0066-4227(2000)54:<849:ROCCIB>2.0.ZU;2-H
Abstract
The gram-positive bacterium Bacillus subtilis is capable of using numerous carbohydrates as single sources of carbon and energy. In this review, we di scuss the mechanisms of carbon catabolism and its regulation. Like many oth er bacteria, B. subtilis uses glucose as the most preferred source of carbo n and energy. Expression of genes involved in catabolism of many other subs trates depends on their presence (induction) and the absence of carbon sour ces that can be well metabolized (catabolite repression). Induction is achi eved by different mechanisms, with antitermination apparently more common i n B. subtilis than in other bacteria. Catabolite repression is regulated in a completely different way than in enteric bacteria. The components mediat ing carbon catabolite repression in B. subtilis are also found in many othe r gram-positive bacteria of low GC content.