Candicanoside A, a novel cytotoxic rearranged cholestane glycoside from Galtonia candicans

Citation
Y. Mimaki et al., Candicanoside A, a novel cytotoxic rearranged cholestane glycoside from Galtonia candicans, HELV CHIM A, 83(10), 2000, pp. 2698-2704
Citations number
5
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Chemistry & Analysis",Chemistry
Journal title
HELVETICA CHIMICA ACTA
ISSN journal
0018-019X → ACNP
Volume
83
Issue
10
Year of publication
2000
Pages
2698 - 2704
Database
ISI
SICI code
0018-019X(2000)83:10<2698:CAANCR>2.0.ZU;2-J
Abstract
A novel cholestane diglycoside, named candicanoside A (1), was isolated fro m the bulbs of Galtonia candicans by monitoring the cytotoxic activity on H L-60 leukemia cells. Candicanoside A (1) is very unique in structure, havin g two epoxy functionalities in its rearranged cholestane skeleton, and show ed differential cytotoxicity in the Japanese Foundation for Cancer Research 38 cell-line assay.