Febrile neutropenia: antifungal prophylaxis

Authors
Citation
Jp. Donnelly, Febrile neutropenia: antifungal prophylaxis, INT J ANT A, 16(2), 2000, pp. 127-130
Citations number
20
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Microbiology
Journal title
INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS
ISSN journal
0924-8579 → ACNP
Volume
16
Issue
2
Year of publication
2000
Pages
127 - 130
Database
ISI
SICI code
0924-8579(200010)16:2<127:FNAP>2.0.ZU;2-R
Abstract
Despite being widely practised there is little or no evidence to support th e use of antifungal prophylaxis in febrile neutropenic patients. With the g reater recognition of risk factor, the increasing readiness to use imaging techniques such as the high resolution CT scan and new methods for detectin g fungi such as Aspergillus galactomannan on the one hand and the widening choice of drugs on the other hand, it may be possible to move away from pro phylaxis towards pre-emptive treatment when the prevalence of fungal diseas e is low. However, the case still has to be proven convincingly by conducti ng formal clinical trials. (C) 2000 Elsevier Science B.V. and International Society of Chemotherapy. All rights reserved.