Factitious hyperkalemia

Citation
Mr. Wiederkehr et Ow. Moe, Factitious hyperkalemia, AM J KIDNEY, 36(5), 2000, pp. 1049-1053
Citations number
21
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Urology & Nephrology
Journal title
AMERICAN JOURNAL OF KIDNEY DISEASES
ISSN journal
0272-6386 → ACNP
Volume
36
Issue
5
Year of publication
2000
Pages
1049 - 1053
Database
ISI
SICI code
0272-6386(200011)36:5<1049:FH>2.0.ZU;2-9
Abstract
Pseudohyperkalemia, or factitious hyperkalemia, constitutes an artificially high plasma potassium level (P-K) from a variety of possible causes, Occas ionally, the cause cannot be elucidated. Three patients who showed unusuall y large differences between free-flowing and tourniquet (stasis) potassium levels prompted us to investigate the influence of tourniquets in routine p hlebotomy in eight healthy volunteers. P-K showed a consistent but rather s mall average increase of 0.2 mEq/L (P < 0.001) during tourniquet use; howev er, the range was 10-fold, from 0.05 to 0.5 mEq/L in our subjects. We sugge st there may be large variability leading to an excessive increase in P-K i n some individuals, In the three patients presented, average excessive incr eases in P-K of 1.6, 1.3, and 1.7 mEq/L were seen. Although diagnosing and treating true hyperkalemia remains paramount, recognizing factitious hyperk alemia is important to preclude unnecessary investigations and potentially hazardous intervention. (C) 2000 by the National Kidney Foundation, Inc.