A simple and efficient method for the synthesis of new chiral polyaza heter
ocylic structures containing pyridines and 1,3-pyrimidine units has been de
veloped. It is based on the reaction of the appropriate enaminones with opt
ically pure carboxamidine derived from the commercially available (R)-(-)-m
yrtenal. (C) 2000 Elsevier Science Ltd. All rights reserved.