Separation factors and thermodynamic data for the separation of various chi
ral analytes on different di-O-tert-butyldimethyl-silylated cyclodextrin de
rivatives are collected and described. Modifying the substitution pattern o
f the tert-butyldimethylsilyl group in position 2 and 3 or changing from be
ta- to gamma-cyclodextrin significantly affects the separation properties o
f the cyclodextrin derivatives.