A comparison of the prognostic significance of tumor diameter, length, width, thickness, area, volume, and clinicopathological features of oral tongue carcinoma

Citation
Apw. Yuen et al., A comparison of the prognostic significance of tumor diameter, length, width, thickness, area, volume, and clinicopathological features of oral tongue carcinoma, AM J SURG, 180(2), 2000, pp. 139-143
Citations number
15
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Surgery,"Medical Research Diagnosis & Treatment
Journal title
AMERICAN JOURNAL OF SURGERY
ISSN journal
0002-9610 → ACNP
Volume
180
Issue
2
Year of publication
2000
Pages
139 - 143
Database
ISI
SICI code
0002-9610(200008)180:2<139:ACOTPS>2.0.ZU;2-7
Abstract
BACKGROUND: The present study aims at evaluation of the prognostic value of tumor size including diameter, length, thickness, width, area, and volume in the prediction of nodal metastasis, local recurrence, and survival of or al tongue carcinoma. The results will have important implications for the m anagement of patients. METHODS: Eighty-five glossectomy specimens of oral tongue carcinoma were se rially sectioned in 3 mm thickness for the tumor size evaluation with compu ter image analyzer. RESULTS: Among all the tumor size parameters being evaluated, tumor thickne ss was the only significant factor for the prediction of local recurrence, nodal metastasis, and survival. With the use of 3 mm and 9 mm division, tum or of up to 3 mm thickness has 10% nodal metastasis, 0% local recurrence, a nd 100% 5-year actuarial disease-free survival; tumor thickness of more tha n 3 mm and up to 9 mm has 50% nodal metastasis, 11% local recurrence, and 7 7% 5-year actuarial disease free survival; tumor of more than 9 mm has 65% nodal metastasis, 26% local recurrence, and 60% 5-year actuarial disease-fr ee survival. CONCLUSIONS: Tumor thickness should be considered in the management of pati ents with oral tongue carcinoma. Am J Surg. 2000;180:139-143. (C) 2000 by E xcerpta Medica, Inc.