Fractal considerations in chromatography: Column efficiency and the multimicrocolumn system

Citation
Yc. Guillaume et al., Fractal considerations in chromatography: Column efficiency and the multimicrocolumn system, J PHYS CH A, 104(39), 2000, pp. 8951-8954
Citations number
23
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Physical Chemistry/Chemical Physics
Journal title
JOURNAL OF PHYSICAL CHEMISTRY A
ISSN journal
1089-5639 → ACNP
Volume
104
Issue
39
Year of publication
2000
Pages
8951 - 8954
Database
ISI
SICI code
1089-5639(20001005)104:39<8951:FCICCE>2.0.ZU;2-F
Abstract
The first part of this paper uses only fractal geometry mathematics to stud y the variations in column efficiency (h) with its geometrical characterist ics (both column and particle diameter,...) and constant column length. In this case the fractal dimension D of h was 2. Conventional results in chrom atography were found with this theory independent of the others. For exampl e, a decrease in the particle diameter filling the column must theoreticall y increase column efficiency. In a second part, geometry was linked to hydr odynamic considerations to study the effect of the microcolumn structure an d its organization in a multimicrocolumn chromatographic system. It demonst rated that to minimize the pressure drop, the geometric structure must obey a power law. This system uses columns with a low diameter and a low pressu re drop to perform efficient separation.