Objectives: to describe the clinical features, management, outcome and labo
ratory features of human immunodeficiency virus (HIV)-related aneurysms.
Materials: twenty-eight HIV positive patients with arterial aneurysms treat
ed at a single university teaching hospital in a 6-year period.
Methods: case review of clinical records and laboratory findings. Specimens
from patients surgically treated submitted for microbiological and histolo
Results: ninety-two aneurysms were seen (range 1-10 per patient) in a young
patient population (median age 30 years). Nineteen patients had evidence o
f advanced HIV infection. Aneurysms were atypically located and most freque
ntly involved the carotid (24), superficial femoral (21) and popliteal (nin
e) arteries. Twenty-five of the 31 symptomatic aneurysms were treated surgi
cally. Surgical intervention comprised arterial vial reconstruction for 29
and aneurysm resection and ligation for the remainder. Histological examina
tion revealed distinctive arteritic features. There were two treatment rela
ted deaths, with short-term post-operative outcome being otherwise favourab
Conclusions: HIV related aneurysms are characterised by their predilection
for young patients, multiplicity, atypical location and their distinct hist
ological features. Their increasing frequency reflects the unchecked advanc
e of the HIV epidemic.