Clinical profile of HIV-related aneurysms

Citation
R. Nair et al., Clinical profile of HIV-related aneurysms, EUR J VAS E, 20(3), 2000, pp. 235-240
Citations number
11
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Surgery
Journal title
EUROPEAN JOURNAL OF VASCULAR AND ENDOVASCULAR SURGERY
ISSN journal
1078-5884 → ACNP
Volume
20
Issue
3
Year of publication
2000
Pages
235 - 240
Database
ISI
SICI code
1078-5884(200009)20:3<235:CPOHA>2.0.ZU;2-9
Abstract
Objectives: to describe the clinical features, management, outcome and labo ratory features of human immunodeficiency virus (HIV)-related aneurysms. Materials: twenty-eight HIV positive patients with arterial aneurysms treat ed at a single university teaching hospital in a 6-year period. Methods: case review of clinical records and laboratory findings. Specimens from patients surgically treated submitted for microbiological and histolo gical examination. Results: ninety-two aneurysms were seen (range 1-10 per patient) in a young patient population (median age 30 years). Nineteen patients had evidence o f advanced HIV infection. Aneurysms were atypically located and most freque ntly involved the carotid (24), superficial femoral (21) and popliteal (nin e) arteries. Twenty-five of the 31 symptomatic aneurysms were treated surgi cally. Surgical intervention comprised arterial vial reconstruction for 29 and aneurysm resection and ligation for the remainder. Histological examina tion revealed distinctive arteritic features. There were two treatment rela ted deaths, with short-term post-operative outcome being otherwise favourab le. Conclusions: HIV related aneurysms are characterised by their predilection for young patients, multiplicity, atypical location and their distinct hist ological features. Their increasing frequency reflects the unchecked advanc e of the HIV epidemic.