Cocaine-associated ischemic colitis

Citation
Jd. Linder et al., Cocaine-associated ischemic colitis, SOUTH MED J, 93(9), 2000, pp. 909-913
Citations number
23
Language
INGLESE
art.tipo
Article
Categorie Soggetti
General & Internal Medicine
Journal title
SOUTHERN MEDICAL JOURNAL
ISSN journal
0038-4348 → ACNP
Volume
93
Issue
9
Year of publication
2000
Pages
909 - 913
Database
ISI
SICI code
0038-4348(200009)93:9<909:CIC>2.0.ZU;2-L
Abstract
Cocaine use can result in various gastrointestinal complications, including gastric ulcerations, retroperitoneal fibrosis, visceral infarction, intest inal ischemia, and gastrointestinal tract perforation. We report cocaine-as sociated colonic ischemia in three patients and review the Literature. Incl uding ours, 28 cases have been reported, with a mean patient age of 32.6 ye ars (range, 23 to 47 years); 53.5% were men and 46.5% were women. The inter val between drug ingestion and onset of symptoms varied from 1 hour to 2 da ys. Cocaine is a potentially life-threatening cause of ischemic colitis and should be included in the differential diagnosis of any young adult or mid dle-aged patient with abdominal pain and bloody diarrhea, especially in the absence of estrogen use or systemic disorders that can cause thromboemboli c events, such as atrial fibrillation.