Cyclic variation of integrated ultrasound backscatter in the left ventricle during the early neonatal period

Citation
K. Mori et al., Cyclic variation of integrated ultrasound backscatter in the left ventricle during the early neonatal period, AM HEART J, 140(3), 2000, pp. 463-468
Citations number
14
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
AMERICAN HEART JOURNAL
ISSN journal
0002-8703 → ACNP
Volume
140
Issue
3
Year of publication
2000
Pages
463 - 468
Database
ISI
SICI code
0002-8703(200009)140:3<463:CVOIUB>2.0.ZU;2-L
Abstract
Background Significant changes in the contractility and histologic structur e of the ventricular myocardium occur during the early neonatal period. Cyc lic variation (CV) of ultrasonic integrated backscatter (IBS) reflects myoc ardial contractile performance. The aim of this study was to define normal values of and its serial changes in CV of IBS in the left ventricle of norm al neonates. Methods and Results We recorded long-axis IBS images in 169 healthy neonate s within 14 days after birth (mean 4.6 +/- 4.2 days) and in 84 infants and children (mean age 8.7 +/- 5.2 years). For each, we obtained CV of IBS in t he interventricular septum (CVIVS) and the posterior wall (CVPW) In neonate s, there was a significant linear correlation between CV and date after bir th in measurements of both the interventricular septum and the posterior wa ll (r = 0.57 and 0.60, respectively). in infants and children, there was no significant relation between age and CVIVS or CVPW. In neonates >4 days af ter birth, the magnitude of CVIVS was not significantly different from that in infants or children. By contrast, the magnitude of CVPW was still signi ficantly decreased in neonates >9 days after birth compared with that in in fants and children (P < .005). The ratio of CVIVS to CVPW (CVIVS/CVPW) was significantly higher in neonates than in infants and children (0.99 +/- 0.2 9 vs 0.80 +/- 0.22, P < .001). Conclusions Both CVIVS and CVPW in neonates gradually increase after birth, indicating developmental maturation of the left ventricle. High valves of CVIVS/CVPW might reflect the remnant of relatively high contractile perform ance in the right ventricle during fetal life.