Flavonol glycosides from Epimedium sagittatum and their neurite outgrowth activity on PC12h cells

Citation
M. Kuroda et al., Flavonol glycosides from Epimedium sagittatum and their neurite outgrowth activity on PC12h cells, PLANTA MED, 66(6), 2000, pp. 575-577
Citations number
13
Language
INGLESE
art.tipo
Letter
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PLANTA MEDICA
ISSN journal
0032-0943 → ACNP
Volume
66
Issue
6
Year of publication
2000
Pages
575 - 577
Database
ISI
SICI code
0032-0943(200008)66:6<575:FGFESA>2.0.ZU;2-Q
Abstract
The MeOH extract of Epimedium sagittatum was found to show neurite outgrowt h activity on cultured PC12h cells. Bioassay-guided fractionation of the Me OH extract yielded six prenylated flavonol glycosides, ikarisoside A (1), i carisid II (2), epimedoside A (3), icariin (4), epimedin B (5), and epimedo koreanoside-I (6) as the active ingredients.