Mucinous carcinoma of the breast with neuroendocrine differentiation

Citation
H. Nakagawa et al., Mucinous carcinoma of the breast with neuroendocrine differentiation, PATHOL INT, 50(8), 2000, pp. 644-648
Citations number
28
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Medical Research Diagnosis & Treatment
Journal title
PATHOLOGY INTERNATIONAL
ISSN journal
1320-5463 → ACNP
Volume
50
Issue
8
Year of publication
2000
Pages
644 - 648
Database
ISI
SICI code
1320-5463(200008)50:8<644:MCOTBW>2.0.ZU;2-#
Abstract
A case of mucinous carcinoma of the breast with neuroendocrine differentiat ion in an 89-year-old woman is presented. The patient presented with a rapi dly growing right breast mass, which she had had for 2-3 years. The tumor, 15 x 8 x 5 cm, was located mainly in the upper outer quadrant. Light micros copy revealed a pure mucinous carcinoma of type B. Neuroendocrine different iation was demonstrated by Grimelius stain and chromogranin A, as well as t he presence of neurosecretory granules. The breast cancer cells were of lum inal origin and had dedifferentiated to attain neuroendocrine properties.