Microvascular ischemia in patients with myotonic dystrophy

Citation
H. Itoh et al., Microvascular ischemia in patients with myotonic dystrophy, JPN CIRC J, 64(9), 2000, pp. 720-722
Citations number
4
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION
ISSN journal
0047-1828 → ACNP
Volume
64
Issue
9
Year of publication
2000
Pages
720 - 722
Database
ISI
SICI code
0047-1828(200009)64:9<720:MIIPWM>2.0.ZU;2-8
Abstract
Two women with myotonic dystrophy underwent dipyridamole thallium-201 (Tl-2 01) myocardial perfusion imaging, after which one patient developed flat T waves in lead I and aVL, and inverted T waves in leads V2-6. The other pati ent developed a nonspecific intraventricular block that progressed to compl ete left bundle branch block and was associated with chest discomfort. Reve rsible scintigraphic defects were observed in both women. Although there wa s evidence that suggested myocardial ischemia on the ECG changes and Tl-201 scintigraphic findings, coronary angiography demonstrated no significant s tenoses in either patient. These findings suggest that microvascular dysfun ction may lead to myocardial ischemia and conduction disturbances in patien ts with myotonic dystrophy.