Effects of weight variability on cardiovascular risk factors; a study of nonsmoking Japanese male office workers

Citation
N. Nakanishi et al., Effects of weight variability on cardiovascular risk factors; a study of nonsmoking Japanese male office workers, INT J OBES, 24(9), 2000, pp. 1226-1230
Citations number
22
Language
INGLESE
art.tipo
Article
Categorie Soggetti
Endocrynology, Metabolism & Nutrition","Endocrinology, Nutrition & Metabolism
Journal title
INTERNATIONAL JOURNAL OF OBESITY
ISSN journal
0307-0565 → ACNP
Volume
24
Issue
9
Year of publication
2000
Pages
1226 - 1230
Database
ISI
SICI code
0307-0565(200009)24:9<1226:EOWVOC>2.0.ZU;2-6
Abstract
OBJECTIVE: To determine the effects of weight variability on cardiovascular risk factors. DESIGN: Longitudinal study (followed from 1990 to 1998), SUBJECTS: Five-hundred and eighty nonsmoking Japanese male office workers a ged 25-49 y. MEASUREMENTS: Baseline levels and slopes of seven selected cardiovascular r isk factors (systolic and diastolic blood pressure, total and high-density lipoprotein cholesterol, triglyceride, uric acid and hemoglobin A(1c)) and body mass index (BMI) variables (baseline BMI, BMI-slope, the root mean squ are error (BMI-RMSE), and the BMI-slope x BMI-RMSE interaction). RESULTS: From the multiple regression analyses, the slopes of the six cardi ovascular risk factors, except hemoglobin A(1c), were most strongly related to the baseline level of each cardiovascular risk factor and BMI-slope, Ne ither BMI-RMSE nor the interaction of BMI-RMSE with BMI-slope was related t o these cardiovascular risk factor slopes. As for hemoglobin A(1c), BMI-slo pe and the interaction of BMI-RMSE with BMI-slope were not significantly re lated to hemoglobin A(1c) slope but baseline BMI and BMI-RMSE were. Further more, hemoglobin A(1c) slope values were significantly higher among those w ho cycled at >4.0 kg than among those who did not. CONCLUSION: The only cardiovascular risk factor associated with BMI variabi lity was hemoglobin A(1c). Weight variability had less or little impact on cardiovascular risk factors compared with BMI-slope and baseline BMI.